Klocalm-Plus HD Tablet is a prescription medicine used to treat anxiety disorder. It calms the brain by decreasing the abnormal and excessive activity of the nerve cells. It blocks the action of certain chemical messengers on the heart and blood vessels. This reduces heart rate and blood pressure. Klocalm-Plus HD Tablet should be taken on an empty stomach. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as it has high habit-forming potential. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly as it may cause withdrawal symptoms. Avoid consuming alcohol while taking this medicine as this may reduce its effectiveness. Some common side effects of this medicine include confusion, memory impairment, slow heart rate, tiredness, and nightmare. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood or depression as this medicine may cause suicidal thoughts. Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.